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DNA ligases seal five′-PO4 and 3′-OH polynucleotide finishes via 3 nucleotidyl transfer ways involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are crucial guardians of genomic integrity, and ligase dysfunction underlies human genetic condition syndromes. Crystal structures of DNA ligases sure to nucleotide and nucleic acid substrates have illuminated how https://dafabet30627.like-blogs.com/27926633/the-single-best-strategy-to-use-for-visit-https-ligaz-bet

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