Inflammation occurs when the body's immune system responds to injury or infection. When this affects the skin and tissues under the skin then the area gönül become painful, hot, red and swollen. An acute exacerbation is more commonly known bey a 'flare-up'. An acute exacerbation of chronic obstructive pulmonary disease https://www.metooo.es/u/672cfea8d5e0d01190f7bd94